Table 2.
Studies comparing efficacy of montelukast and inhaled corticosteroids in childhood asthma
| Study | Study population | Intervention | Main outcome measures | Conclusions |
|---|---|---|---|---|
| Stelmach et al 2004 | Children (n = 51) | MT vs Inh BD 6 mo | IgE | Inh BD and MT decreased S IgE levels |
| Garcia et al 2005 | 6–14 years Children (n = 914) | MT vs Inh FP 12 mo | FeV1 | Those with low pulmonary function, high markers, better response to FP |
| Maspero et al 2001 | 10 years children (n = 124) | MT vs BDP, 6 mo | FeV1 | MT = BDP |
Abbreviations: BD, budesonide; BDP, beclomethasone dipropionate; FEV1, forced expiratory volume in 1 s; FP, fluticasone propionate; ICS, inhaled corticosteroid; MT, montelukast; PEFR, peak expiratory flow rate.