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. 2002 Jul 2;87(2):238–245. doi: 10.1038/sj.bjc.6600424

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Copyright © 2002 Cancer Research UK

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Intracellular pH (pHi) of MCF7 cells (light histograms) and MDA-MB231 cells (dark histograms) following a 24-h incubation period in media adjusted to different pHe (7.4 or 6.8) in the absence or presence of S3705 and cariporide (SC). The results indicated are the mean±s.e.m. of at least three experiments. Student t-test indicates that the pHi of the cells incubated in the presence of the inhibitors is lower than the pHi of cells incubated at the same pHe in their absence (i.e. 7.4 vs 7.4SC, 6.8 vs 6.8SC) (P⩽0.02, both comparisons).