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. 2002 Nov 4;87(10):1145–1152. doi: 10.1038/sj.bjc.6600578

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Copyright © 2002 Cancer Research UK

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(A) Squamous cervical cancer with intense COX-2 immunoreaction in both cytoplasm and nuclei of tumour cells. Scattered cells in the stromal compartment are stained. (B) COX-2 negative tumour showing intense COX-2 staining in the stroma inflammatory compartment. CD3, CD4, CD25, and tryptase immunoreaction in tumours showing high (C, E, G) vs low (D, F, H) tumour/stroma COX-2 IDV ratio. Bar=50 μm (A,B); Bar=25 μm (C–H).