2.
Retinal arteriolar velocity, mean circulation time, and pressure data.
Group | Control | STZ-injected | |
---|---|---|---|
Retinal arteriolar velocity (mm/s) | 4 week | 23.0 ± 0.5 | 17.6 ± 0.4*** |
8 week | 22.5 ± 0.4 | 17.7 ± 0.4*** | |
Mean Arterial Pressure (mmHg) | 4 week | 68.2 ± 2.0 | 68.2 ± 2.0 |
8 week | 66.9 ± 2.9 | 82.2 ± 3.2**, † | |
Intraocular Pressure (mmHg) | 4 week | 11.6 ± 0.4 | 11.7 ± 0.8 |
8 week | 12.6 ± 0.3 | 11.3 ± 0.9 | |
Mean Circulation Time (ms) | 4 week | 969 ± 111 | 1191 ± 193 |
8 week | 927 ± 170 | 1066 ± 90 |
Velocity data were obtained from N=27–71 arterioles using 5–13 mice per group. Mean arterial pressure (N=4–7 mice per group); Intraocular pressure (N=5–8 mice per group); Mean circulation time (N=5–9 mice per group).
p<0.001: STZ vs Control
p<0.01: STZ vs Control
p<0.05: 8 week STZ vs 4 week STZ.