FIGURE 9.

Rotary shadowing electron microscopy depicting binding of the BMP-7 complex to the N-terminal half of fibrillin-1 (rF90). A, rotary shadowing electron microscopy showed globular molecules of BMP-7 complex bound to the very end of rF90. Images of individual molecules shadowed alone are shown for rF90 (B) and the BMP-7 complex (C). Scale bar = 25 nm. D, the lengths of rF90 molecules peaked at 90 nm (n = 122), whereas the peak lengths of rF90 + BMP-7 complex composites were 100–105 nm (n = 36).