Skip to main content
. 2008 May 16;283(20):13538–13548. doi: 10.1074/jbc.M709950200

FIGURE 3.

FIGURE 3.

Weight gain and fat accumulation in WT and PAI-1–/– mice after 16 weeks on a LFD or HFD. A, PAI-1 mRNA expression as determined by real time reverse transcription-PCR in epididymal and subcutaneous fat pads. Data are means (n = 6) ± S.D. For both epididymal and subcutaneous fat pads, HFD versus LFD, p < 0.01. B, body weight gain in WT and PAI-1–/– mice. Data are means (n = 8) ± S.D. WT versus PAI-1–/– mice on HFD, p < 0.01. C, abdominal subcutaneous fat pad weights of WT and PAI-1–/– mice. Data are means (n = 8) ± S.D. WT versus PAI-1–/– mice on HFD, p < 0.01. D, epididymal fat pad weights of WT and PAI-1–/– mice. Data are means (n = 8) ± S.D. WT versus PAI-1–/– mice on HFD, p < 0.05. E, hematoxylin and eosin-stained histological sections (×200) of epididymal and subcutaneous fat pads from WT and PAI-1–/– mice. Results are representative of n = 6 in each group. Upper panels, epididymal fat; lower panels, subcutaneous fat.