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Inhibitor susceptibility. The indicated inhibitors were preincubated in duplicate with wild type recombinant guinea pig chymase (guinea pig), partially humanized recombinant guinea pig chymase (A216G), bovine chymotrypsin, and recombinant human chymase and then assayed for residual peptidyl 4-NA-hydrolyzing activity. The graph shows mean percentage inhibition as compared with the enzymes preincubated without added inhibitor.
