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. 2002 Dec 2;87(12):1431–1436. doi: 10.1038/sj.bjc.6600653

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Copyright © 2002 Cancer Research UK

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Immunhistochemical staining of serial tissue sections of a nodular melanoma, tumour thickness according to Breslow 1.4 mm, Clark's level IV. The PTEN/MMAC1 protein was detected in melanoma cells and was not restricted to tumour associated macrophages. (a) Hematoxylin Eosin, (b) HMB45, (c) CD68, (d) PTEN/MMAC1 staining (all magnification 25×, nickel enhanced DAB reaction resulting in black signals).