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. 2003 Mar 4;88(5):782–787. doi: 10.1038/sj.bjc.6600809

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Copyright © 2003 Cancer Research UK

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Concentration–time profiles of capecitabine and its metabolites in one patient on day 12. Patients received 1250 mg capecitabine m⁻² orally with tap water before collecting plasma samples and interstitial tissue fluid up to 5 h after administration. Concentration–time profile in plasma (A), concentration–time profile in the interstitium of malignant tissue (B), concentration–time profile in the interstitium of subcutaneous connective tissue (C).