Table 1. Expression patterns of IGF-2 and M6P/IGF-2R.
IGF-2 RNA-pattern | ||||||
---|---|---|---|---|---|---|
Case no. | Aetiology | Histology | HC diffuse | HC clusters | BDC | M6P/IGF-2R |
1 | HBV | Cirrhosis | + | ++++ | 0 | + |
2 | HBV | Cirrhosis | + | ++++ | 0 | + |
3 | HBV | Cirrhosis | + | ++++ | 0 | + |
4 | HBV | Cirrhosis | + | ++++ | 0 | + |
5 | HBV | Cirrhosis | + | ++++ | 0 | + |
6 | HBV | Cirrhosis | + | ++++ | 0 | + |
7 | HBV/HDV | Cirrhosis | + | ++++ | 0 | + |
8 | HCV | Cirrhosis | + | ++++ | 0 | + |
9 | HCV | Cirrhosis | + | ++++ | ++++ | + |
10 | HCV | Cirrhosis | + | ++++ | 0 | + |
11 | AI | Cirrhosis | + | ++ | 0 | + |
12 | AI | Cirrhosis | + | 0 | 0 | + |
13 | Alc | Cirrhosis | + | 0 | 0 | + |
14 | Alc | Cirrhosis | + | 0 | 0 | + |
15 | Alc | Cirrhosis | + | 0 | 0 | + |
16 | Alc | Cirrhosis | + | 0 | 0 | + |
17 | PBC | Cirrhosis | + | 0 | 0 | + |
18 | PSC | Cirrhosis | + | 0 | 0 | + |
19–21 | Regular | 0 | 0 | 0 | ++ |
AI=autoimmune hepatitis; Alc=alcohol-induced hepatitis; BDC=bile duct cells; HC=hepatocytes; PSC=primary sclerosing cholangitis; PBC=primary biliary cirrhosis; − and + to +++=average signal intensity relative to background labelling: −=background; +=1–2x; ++=2–5x; +++=5–10x; ++++=>10x background (background signal=5 five grains for BDC and 10 grains for HC).