Table 3. Relative risks for colorectal cancer according to BMI.
|
Men, BMI (kg m−2) |
||||
|---|---|---|---|---|
| ⩽21.2 | 21.3–22.4 | ⩾23.6 | P for trend | |
| Colon cancer | ||||
| Person-years | 32 685 | 33 839 | 33 772 | |
| Number | 26 | 35 | 43 | |
| Age-adjusted RRs (95% CI) | 1.00 | 1.47 (0.88–2.44) | 1.98 (1.21–3.25) | 0.007 |
| Multivariate RRs (1) (95% CI) | 1.00 | 1.46 (0.87–2.46) | 2.07 (1.26–3.42) | 0.004 |
| Multivariate RRs (2) (95% CI) | 1.00 | 1.57 (0.92–2.68) | 2.11 (1.26–3.53) | 0.005 |
| Rectal cancer | ||||
| Person-years | 32 669 | 33 687 | 33 728 | |
| Number | 24 | 18 | 16 | |
| Age-adjusted RRs (95% CI) | 1.00 | 0.85 (0.46–1.56) | 0.85 (0.45–1.60) | 0.60 |
| Multivariate RRs (1) (95% CI) | 1.00 | 0.76 (0.40–1.44) | 0.79 (0.41–1.52) | 0.47 |
| Multivariate RRs (2) (95% CI) | 1.00 | 0.80 (0.41–1.55) | 0.83 (0.42–1.64) | 0.59 |
|
Women, BMI (kg m−2) |
||||
| ⩽21.6 | 21.7–23.0 | ⩾23.1 | P for trend | |
| Colon cancer | ||||
| Person-years | 35 100 | 35 905 | 36 373 | |
| Number | 28 | 25 | 36 | |
| Age-adjusted RRs (95% CI) | 1.00 | 1.06 (0.61–1.82) | 1.14 (0.68–1.90) | 0.62 |
| Multivariate RRs (1) (95% CI) | 1.00 | 1.08 (0.58–2.00) | 1.26 (0.72–2.22) | 0.39 |
| Multivariate RRs (2) (95% CI) | 1.00 | 1.02 (0.55–1.91) | 1.22 (0.69–2.15) | 0.48 |
| Rectal cancer | ||||
| Person-years | 25 046 | 35 836 | 36 290 | |
| Number | 14 | 12 | 15 | |
| Age-adjusted RRs (95% CI) | 1.00 | 0.77 (0.35–1.71) | 0.92 (0.44–1.92) | 0.86 |
| Multivariate RRs (1) (95% CI) | 1.00 | 0.86 (0.36–2.02) | 0.98 (0.44–2.20) | 0.99 |
| Multivariate RRs (2) (95% CI) | 1.00 | 0.84 (0.36–1.99) | 0.83 (0.35–1.99) | 0.68 |
Multivariate (1)=adjusted for age, height, alcohol consumption, smoking, and years of education. Multivariate (2)=adjusted for age, height, alcohol consumption, smoking, years of education, and physical activity. CI=confidence interval.