Table 4. Relative risks for colorectal cancer according to alcohol consumption.
|
Men, alcohol intake |
||||
|---|---|---|---|---|
| No alcohol | ⩽36.7 g day−1 | >36.7 g day−1 | P for trend | |
| Colon cancer | ||||
| Person-years | 8088 | 46 494 | 47 424 | |
| Cases, n | 5 | 45 | 58 | |
| Age-adjusted RRs (CI) | 1.00 | 1.94 (0.77–4.90) | 2.96 (1.17–7.46) | 0.007 |
| Multivariate RRs (CI) | 1.00 | 1.79 (0.71–4.55) | 2.67 (1.06–6.76) | 0.01 |
| Rectal cancer | ||||
| Person-years | 8114 | 46 379 | 47 289 | |
| Cases, n | 8 | 20 | 31 | |
| Age-adjusted RRs (CI) | 1.00 | 0.57 (0.25–1.30) | 1.12 (0.50–2.51) | 0.06 |
| Multivariate RRs (CI) | 1.00 | 0.59 (0.25–1.42) | 1.17 (0.50–2.73) | 0.06 |
|
Women, alcohol intake |
||||
| No alcohol | ⩽3.75 g day−1 | >3.75 g day−1 | P for trend | |
| Colon cancer | ||||
| Person-years | 36 265 | 36 394 | 36 416 | |
| Cases, n | 34 | 28 | 32 | |
| Age-adjusted RRs (CI) | 1.00 | 0.87 (0.51–1.49) | 1.52 (0.92–2.53) | 0.04 |
| Multivariate RRs (CI) | 1.00 | 1.07 (0.58–1.96) | 1.78 (1.00–3.18) | 0.03 |
| Rectal cancer | ||||
| Person-years | 36 131 | 36 325 | 36 385 | |
| Cases, n | 7 | 15 | 19 | |
| Age-adjusted RRs (CI) | 1.00 | 1.88 (0.74–4.79) | 2.27 (0.91–5.69) | 0.17 |
| Multivariate RRs (CI) | 1.00 | 1.20 (0.44–3.26) | 1.80 (0.70–4.62) | 0.17 |
Multivariate=adjusted for age, height, BMI, smoking, and years of education.