Table 2.

First semantic and behavioral symptoms in temporal variant frontotemporal dementia

	First symptom type
Patient	Semantic	Behavioral
LTLV
1	Anomia for people, places, objects*	(Disinhibition, compulsions)
2	Anomia for people, repetitive speech*	Irritability*
3	Anomia for people, places, objects*	Insomnia, emotional withdrawal
4	Word-finding difficulties*	(Weight gain)
5	Word-finding difficulties, anomia for objects	Hostility/irritability toward husband*
6	Word-finding difficulties*	Depression, irritability, suspiciousness, stubbornness, insensitivity
RTLV
1	Impaired reading/word comprehension	Depression, poor appetite, weight loss, insomnia*
2	Anomia for people, places, objects*	Apathy
3	Anomia for people	Emotional withdrawal*
4	Anomia for people	Apathy, loss of sexual interest, increased alcohol intake*
5	Anomia, word comprehension*	Irritability*
6	Impaired word comprehension	Emotional blunting*

^*Symptoms were patients’ first overall and were used to define the first symptom clusters. Symptoms in parentheses were patients’ first symptoms within the listed symptom type but were never first overall symptoms.

LTLV = left temporal lobe variant; RTLV = right temporal lobe variant.