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. 2003 Jan 28;88(1):96–101. doi: 10.1038/sj.bjc.6600656

Table 1. Prognostic factors related to axillary lymph node invasion in early (T1) breast cancer: Univariate analysis.

  Number of women No. of women with positive nodes (%) OR 95% CI P-value
           
Histologic type
Ductal 178 47 (26%) 1    
Lobular 16 5 (31%) 1.26 0.42–3.84 0.676
Tubular 10 0 (0%) 0.00 0.00–1.09 0.069
Rest of types 8 2 (25%) 0.93 0.18–4.76 0.930
           
Tumour size
>1 cm 152 45 (30%) 1    
1–0.6 cm 51 9 (18%) 0.51 0.23–1.13 0.098
⩽0.5 cm 9 0 (0%) 0.00 0.00–1.04 0.063
           
uPA–PAI-1
0 55 10 (18%) 1    
1–4 48 15 (31%) 2.04 0.82–5.12 0.126
5–6 86 25 (29%) 1.84 0.81–4.22 0.148
Unknown 23 4 (17%) 0.80 0.26–3.40 0.934
           
Hormone receptors
ER−PR− 61 14 (23%) 1    
ER+PR− 24 7 (29%) 1.38 0.48–4.00 0.551
ER+PR+ 124 33 (27%) 1.21 0.59–2.49 0.591
Unknown 3 0 (0%) 0.00 0.00–4.68 1.000
           
Nuclear grade
1 and 2 122 32 (26%) 1    
3 57 16 (28%) 1.10 0.54–2.22 0.796
Unknown 33 6 (18%) 0.63 0.24–1.65 0.343
           
Histologic grade
1 and 2 139 31 (22%) 1    
3 40 17 (43%) 2.58 1.22–5.41 0.013
Unknown 33 6 (18%) 0.77 0.29–2.04 0.605
           
Ki67
⩽10% 89 16 (18%) 1    
>10% 99 35 (35%) 2.50 1.26–4.93 0.008
Unknown 24 3 (13%) 0.65 0.17–2.45 0.527
           
c-erb-B2
Negative 159 43 (27%) 1    
Positive 27 7 (26%) 0.94 0.37–2.39 0.904
Unknown 26 4 (15%) 0.49 0.16–1.51 0.213
           
p53
Negative 154 41 (27%) 1    
Positive 35 10 (29%) 1.10 0.49–2.49 0.815
Unknown 23 3 (13%) 0.41 0.13–1.46 0.171
           
CD44
3–6 110 18 (16%) 1    
1–2 22 5 (23%) 1.50 0.49–4.60 0.475
Negative 50 25 (50%) 5.11 2.41–10.8 <0.001
Unknown 30 6 (20%) 1.28 0.45–3.57 0.640