Table 1. Description of clinicopathological data and the association with the Chalkley count, PAI-1 levels and uPA levels.
| Chalkley count | PAI-1 | uPA | |||
|---|---|---|---|---|---|
| (points) | (ngmg−1 total protein) | (ngmg−1 total protein) | |||
| Variables | N | (%) | Median | Median | Median |
| All | 228 | (100) | 6.0 | 11.05 | 4.65 |
| Age (years) | |||||
| <40 | 11 | (5) | 6.3 | 11.4 | 4.2 |
| 40–49 | 41 | (18) | 6.1 | 10.7 | 3.3 |
| 50–59 | 51 | (22) | 6.0 | 10.1 | 5.0 |
| 60–69 | 60 | (26) | 6.3 | 11.3 | 4.9 |
| ⩾70 | 65 | (29) | 5.7 | 11.3 | 5.5 |
| P=0.99 | P=0.90 | P=0.69 | |||
| Menopausal status | |||||
| Pre | 68 | (30) | 6.2 | 10.6 | 4.2 |
| Post | 160 | (70) | 6.0 | 11.3 | 5.0 |
| P=0.86 | P=0.31 | P=0.27 | |||
| Tumour size (mm) | |||||
| ⩽20 | 86 | (38) | 5.7 | 10.5 | 3.8 |
| 21–50 | 132 | (58) | 6.3 | 12.7 | 5.7 |
| >50 | 10 | (4) | 6.5 | 8.1 | 3.0 |
| P=0.004 | P=0.019 | P=0.004 | |||
| Histological malignancy grade | |||||
| I (ductal) | 36 | (16) | 5.2 | 9.6 | 4.4 |
| II (ductal) | 87 | (38) | 6.0 | 12.1 | 5.4 |
| III (ductal) | 74 | (32) | 7.0 | 12.9 | 5.5 |
| Other (nonductal) | 31 | (14) | 5.1 | 5.1 | 1.8 |
| P<0.001 | P<0.001 | P<0.001 | |||
| Receptor status | |||||
| Positive | 174 | (76) | 5.7 | 10.8 | 4.5 |
| Negative | 54 | (24) | 7.7 | 12.9 | 5.6 |
| P<0.001 | P=0.027 | P=0.069 | |||
| Lymph node metastasis | |||||
| None | 101 | (44) | 6.0 | 9.7 | 4.2 |
| 1–3 | 78 | (34) | 6.0 | 12.5 | 5.4 |
| ⩾4 | 49 | (22) | 6.7 | 14.7 | 5.2 |
| P=0.82 | P=0.008 | P=0.055 | |||
Significant associations are given in bold.