. Author manuscript; available in PMC: 2008 May 12.

Published in final edited form as: Nat Cell Biol. 2008 Jan 20;10(2):138–148. doi: 10.1038/ncb1676

Table 2.

MDM2+ and FOXO3a− is associated with higher tumour grade in breast cancer patients.

Combined	Tumour grade		Total
	Low	High
MDM2− FOXO3a−	0 (0.0)	17 (16.50)	17
MDM2+ FOXO3a−	9 (40.91)	52 (50.49)	61
MDM2− FOXO3a+	7 (31.82)	13 (12.62)	20
MDM2+ FOXO3a+	6 (27.27)	21 (20.39)	27
Total	22	103	125

The relationship between combined expression of FOXO3a and MDM2 and tumour grade in human breast cancer specimens was analysed using a χ-square test. A P value of <0.05 was considered statistically significant.