Table 1. Association of MMP-7 expression and clinicopathologic findings.

	MMP-7			MMP-7 at invasive front
	Positive	Negative	P	Positive	Negative	P
Variables	(n=13)	(n=42)	value	(n=7)	(n=48)	value
Gender
Male	11	30	0.447	6	35	0.664
Female	2	12		1	13
Age
≦59	2	14	0.461	1	15	0.851
60–64	4	5		3	6
65–69	3	7		2	8
70≦	4	16		1	19
Gross features
Elevated	4	7	0.291	3	8	0.057
Flat	1	1		1	1
Depressed	8	34		3	39
Depth of invasion
EP	0	9	0.06	0	9	0.013*
LPM	2	4		0	6
MM	2	14		0	16
SM	9	15		7	17
Differentiation grade
SCC (well)	2	8	0.569	0	10	0.334
SCC (moderately)	9	22		6	25
SCC (poorly)	1	10		1	10
Others	1	2		0	3
Lymphatic permeation
Positive	8	13	0.059	6	15	0.01*
Negative	5	29		1	33
Venous invasion
Positive	1	7	0.664	1	7	1
Negative	12	35		6	41
Infiltrative growth pattern
α	4	24	0.186	1	27	0.043*
β	8	17		5	20
γ	1	1		1	1
Nodal metastasis
Positive	7	5	0.004*	5	7	0.004*
Negative	6	37		2	41

^*Significant.