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. 2003 Nov 25;89(11):2045–2050. doi: 10.1038/sj.bjc.6601364

Table 3. Univariate survival analysis.

Characteristic Categories Patients(no) Survival median (months) 1-year (%) Logrank P
Age (years) <60 215 9 29 0.235
  Δ60 135 11 39  
           
Gender Female 72 11 42 0.390
  Male 278 9 30  
           
Performance status (WHO) 0 66 12 45 <0.001a
  1 219 10 35  
  2 63 5 13  
           
Weight loss (%) Ω 5 121 12 39 0.006a
  5–10 91 9 32  
  Δ 10 131 9 29  
           
Tumor type SCC 199 9 32 0.550
  Adenoca 145 10 32  
           
Tumor differentiationb Well/moderate 119 10 43 0.102
  Poor 131 9 28  
           
Liver metastasis No 269 10 37 <0.001
  Yes 81 7 21  
           
No. of metastatic sites 0 42 10 36 0.02a
  1 190 10 34  
  >1 118 7 31  
           
Extent of disease Locoregional 42 10 36 < 0.001c
  Limited dissem. 138 12 41 < 0.001c
  Extensive dissem. 170 7 26  
           
Interval between diagnosis and start treatment <6 months 295 10 34 0.65
  >6 months 55 8 27  
           
Haemoglobin Normal 228 10 36 0.253
  Abnormal 122 9 28  
           
Alkaline phosphatase Normal 246 10 37 0.001
  Elevated 104 7 24  
           
LDH Normal 296 11 46 <0.001
  Elevated 54 8 16  
           
Paclitaxel Yes 139 10 40 0.002
  No 211 9 29  
a

Trend test,

b

tumour differentiation was unknown in 100 patients,

c

vs extended dissemination.