Table 3. Univariate survival analysis.
Characteristic | Categories | Patients(no) | Survival median (months) | 1-year (%) | Logrank P |
---|---|---|---|---|---|
Age (years) | <60 | 215 | 9 | 29 | 0.235 |
Δ60 | 135 | 11 | 39 | ||
Gender | Female | 72 | 11 | 42 | 0.390 |
Male | 278 | 9 | 30 | ||
Performance status (WHO) | 0 | 66 | 12 | 45 | <0.001a |
1 | 219 | 10 | 35 | ||
2 | 63 | 5 | 13 | ||
Weight loss (%) | Ω 5 | 121 | 12 | 39 | 0.006a |
5–10 | 91 | 9 | 32 | ||
Δ 10 | 131 | 9 | 29 | ||
Tumor type | SCC | 199 | 9 | 32 | 0.550 |
Adenoca | 145 | 10 | 32 | ||
Tumor differentiationb | Well/moderate | 119 | 10 | 43 | 0.102 |
Poor | 131 | 9 | 28 | ||
Liver metastasis | No | 269 | 10 | 37 | <0.001 |
Yes | 81 | 7 | 21 | ||
No. of metastatic sites | 0 | 42 | 10 | 36 | 0.02a |
1 | 190 | 10 | 34 | ||
>1 | 118 | 7 | 31 | ||
Extent of disease | Locoregional | 42 | 10 | 36 | < 0.001c |
Limited dissem. | 138 | 12 | 41 | < 0.001c | |
Extensive dissem. | 170 | 7 | 26 | ||
Interval between diagnosis and start treatment | <6 months | 295 | 10 | 34 | 0.65 |
>6 months | 55 | 8 | 27 | ||
Haemoglobin | Normal | 228 | 10 | 36 | 0.253 |
Abnormal | 122 | 9 | 28 | ||
Alkaline phosphatase | Normal | 246 | 10 | 37 | 0.001 |
Elevated | 104 | 7 | 24 | ||
LDH | Normal | 296 | 11 | 46 | <0.001 |
Elevated | 54 | 8 | 16 | ||
Paclitaxel | Yes | 139 | 10 | 40 | 0.002 |
No | 211 | 9 | 29 |
Trend test,
tumour differentiation was unknown in 100 patients,
vs extended dissemination.