Table 3. Factors associated with tumour regression ⩾50%, including complete tumour regression after six cycles of primary chemotherapy among 125 patients: multivariate analyses (model 1: factors identified in MacGrogan 1996a; model 2: with new factor, Ki-S7).
|
Model 1 |
Model 2 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| B | Standard error | OR | 95 CI | P | B | Standard error | OR | 95 CI | P | |
| Clinical tumour size | ||||||||||
| >40 mm | Reference | Reference | ||||||||
| ⩽40 mm | 1.327 | 0.451 | 3.771 | 1.55–9.12 | 0.003 | 1.342 | 0.450 | 3.82 | 1.58–9.25 | 0.002 |
| IHC-ER | ||||||||||
| ⩾10% | Reference | Reference | ||||||||
| <10% | 1.212 | 0.436 | 3.362 | 1.43–7.9 | 0.005 | 1.210 | 0.435 | 3.35 | 1.43–7.86 | 0.005 |
| Ki-67 | ||||||||||
| ⩽40% | Reference | Excluded from model | 0.092 | |||||||
| >40% | 1.364 | 0.528 | 3.910 | 1.39–10.99 | 0.010 | |||||
| Ki-S7 | ||||||||||
| ⩽15% | – | – | – | – | – | Reference | ||||
| >15% | – | – | – | – | – | 1.208 | 0.441 | 3.347 | 1.41–7.93 | 0.006 |
Each of the odds ratios is adjusted for all other variables in the table. OR=odd ratio. 95 CI=95% confidence interval.