Table 1. Clinical features of the patients.
Case (no) | Age (years) | Sex | WBC (l−1) | Phenotype | DNA index | Karyotype | Follow-up |
---|---|---|---|---|---|---|---|
1 | 11 | F | 21 × 109 | cALL | 1,00 | 46,XX | +8 CR |
2 | 2 | M | 11 × 106 | cALL | 1,20 | 53, XY,+4,+6,+8,+12,+20+21+21+21 | +8 CR |
3 | 13 | F | 14 × 106 | Pre-Pre-B-ALL | 1,00 | 46,XX | +5 CR |
4 | 4 | F | 11 × 106 | cALL | 1,06 | 50,XX,+21[c] | +5 CR |
5 | <1 | F | 13 × 106 | Pre-B-ALL | 1,00 | 46,XX,+8,+19,+22 | +4 CR |
6 | 3 | M | 7,9 × 106 | cALL | 1,00 | 47,XY,del(14q21),+marker | +5 CR |
7 | 4 | M | 350 × 106 | cALL | 1,00 | 46,XY t (9;22) | Resistant |
8 | 10 | F | 27 × 106 | cALL | 1,21 | 58,XX,+ × ,+1,+3,+8,+14,+16,+18,21,+19,+19,+21,+21,+21/46,XX | +30 CR |
9 | 9 | M | 140 × 106 | Pre-pre-B ALL | 1,00 | 46,XY t (4;11)/47,XY | +38 CR |
10a | F | 11 × 106 | cALL | ND | ND | Exitus | |
11a | 7 | M | 13 × 106 | Pre-B ALL | 1,00 | 46, XY | Exitus |
12a | 5 | F | 132 × 106 | LLA B mature | 1,00 | No mitosis | +2 TMO |
13a | 3 | M | 58 × 109 | cALL | 1,00 | ND | Exitus |
14a | 9 | M | 35 × 109 | Null ALL | ND | 46,XY | Exitus |
=relapse. ND=not determined.