Table 2. Stroma-supported immunocytometric assay % cell death after 7 days Aplidin exposure.
Aplidin (nM) |
||||
---|---|---|---|---|
Patient no | 0.005 nM | 0.05 nM | 0.05 nM | 5 nM |
1 | NT | 12 | 22 | 96 |
2 | NT | 79 | 79 | 100 |
3 | 14 | 20 | 40 | 99 |
4 | 16 | 36 | 60 | 100 |
5 | 12 | 19 | 46 | 100 |
6 | <1 | <1 | 9 | 96 |
7 | <1 | <1 | <1 | 74 |
8 | <1 | <1 | <1 | 97 |
9 | <1 | <1 | <1 | 90 |
10a | 31 | 3 | 35 | 82 |
11a | <1 | 1 | 49 | 98 |
12a | 10 | 9 | 99 | 88 |
13a | 47 | 33 | 55 | 97 |
14a | <1 | ND | 50 | 97 |
=relapse. ND=not determined.