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. 2003 Aug 12;89(4):691–696. doi: 10.1038/sj.bjc.6601075

Table 3. Relation between Arg462Gln and Asp541Glu genotypes and pathological grade.

  No. of subjects (%)
   
  Gleason score
   
Genotype <7 ⩾7 OR (95% CI) P-value
Arg462Gln        
 Arg/Arg 19 (76.0%) 50 (65.8%) 1.0 (Ref.)  
 Arg/Gln 6 (24.0%) 26 (34.2%) 1.65 (0.94–2.87) 0.69
 Gln/Gln 0 (0.0%) 0 (0.0%)    
         
Asp541Glu        
 Glu/Glu 14 (56.0%) 37 (48.7%) 1.0 (Ref.)  
 Glu/Asp 9 (36.0%) 23 (30.3%) 0.97 (0.55–1.69) 0.95
 Asp/Asp 2 (8.0%) 16 (21.1%) 3.03 (1.74–5.28) 0.16
         
 Glu/Glu+Glu/Asp 23 (92.0%) 60 (78.9%) 1.0 (Ref.)  
 Asp/Asp 2 (8.0%) 16 (21.1%) 3.07 (1.76–5.35) 0.14