Table 4. The Cox model applied to the ovarian data, with a time dependency added to ascites and endometroid terms.
Covariate | Coefficient (bi) | HR [exp(bi)] | 95% CI | P-value |
---|---|---|---|---|
FIGO | 0.734 | 2.09 | (1.83–2.38) | <0.001 |
Histology | <0.001 | |||
Serous | (0.000) | (1.00) | ||
Mucinous | −0.432 | 0.65 | (0.50–0.85) | |
Clear cell | 0.344 | 1.41 | (0.99–2.01) | |
Adenocarcinoma | 0.494 | 1.64 | (0.91–2.96) | |
Undifferentiated | 0.769 | 2.16 | (1.06–4.40) | |
Mixed mesodermal | 0.825 | 2.28 | (1.50–3.47) | |
Endometroid | 0.312 | 1.37 | (0.90–2.07) | |
Endometroid × log(time) | −0.500 | 0.61 | (0.45–0.82) | 0.001 |
Grade | <0.001 | |||
1 | (0.000) | (1.00) | ||
2 | 0.826 | 2.28 | (1.32–3.95) | |
3 | 0.843 | 2.32 | (1.35–4.00) | |
Absence of ascites | −0.466 | 0.63 | (0.50–0.80) | <0.001 |
Ascites × log(time) | 0.233 | 1.26 | (1.01–1.58) | 0.04 |
Age (per 5-year increase) | 0.134 | 1.14 | (1.09–1.20) | <0.001 |
R=hazard ratio; CI=confidence interval.