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. 2003 Aug 12;89(4):746–753. doi: 10.1038/sj.bjc.6601161

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Copyright © 2003 Cancer Research UK

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Dose–response effects of 1α,25(OH)₂D₃ (A) or 19-nor-1α,25(OH)₂D₂ (B) alone, or combined with IR on the growth of LNCaP prostate tumour cells. Cells were plated in medium and drugs were added 24 h later. Cells were irradiated 24 h following addition of 1α,25(OH)₂D₃ or 19-nor-1α,25(OH)₂D₂ and allowed to grow for an additional 7 days, at which time MTT assay was performed as described in Materials and Methods. Optical density (OD) values represent the average of four readings per experiment. Each experiment was performed three times. Error bars represent s.e. values.