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. 2003 Sep 9;89(6):971–976. doi: 10.1038/sj.bjc.6601235

Table 4. Comparison of selected quality of life items during 12 months of androgen deprivation expressed as means and standard errors (s.e).

Symptom Baseline 6 months 12 months  
scales/items Mean (s.e.) Mean (s.e.) Mean (s.e.) P-value
Fatigue 14.3 (3.08) 19.7 (4.10) 20.5 (4.30) 0.044
Dyspnoea 8.57 (3.70) 13.6 (3.67) 17.2 (4.57) 0.030
Insomnia 21.6 (4.42) 34.6 (4.87) 34.5 (5.36) 0.1071
Diarrhoea 4.76 (2.00) 17.3 (5.15) 17.2 (4.26) 0.001
Erectile dysfunction 221 (1.07) 3.08 (1.06) 3.32 (0.86) 0.0002
Gynaecomastia 1.23 (0.08) 1.46 (0.15) 1.46 (0.12) 0.0005
Libido 1.83 (0.16) 3.00 (0.20) 3.10 (0.18) <0.0001
Male identity 1.96 (0.96) 3.28 (0.74) 3.00 (1.07) 0.0011
Depressive mood 1.77 (0.16) 1.54 (0.13) 1.77 (0.16) 0.8567
Spouse relationship 1.32 (0.10) 1.64 (0.18) 1.48 (0.16) 0.2332
Urinary frequency 2.25 (0.89) 2.15 (0.73) 2.00 (0.82) 0.0425a
a

Other items worsened, this item improved significantly.