Table 4. Comparison of selected quality of life items during 12 months of androgen deprivation expressed as means and standard errors (s.e).
Symptom | Baseline | 6 months | 12 months | |
---|---|---|---|---|
scales/items | Mean (s.e.) | Mean (s.e.) | Mean (s.e.) | P-value |
Fatigue | 14.3 (3.08) | 19.7 (4.10) | 20.5 (4.30) | 0.044 |
Dyspnoea | 8.57 (3.70) | 13.6 (3.67) | 17.2 (4.57) | 0.030 |
Insomnia | 21.6 (4.42) | 34.6 (4.87) | 34.5 (5.36) | 0.1071 |
Diarrhoea | 4.76 (2.00) | 17.3 (5.15) | 17.2 (4.26) | 0.001 |
Erectile dysfunction | 221 (1.07) | 3.08 (1.06) | 3.32 (0.86) | 0.0002 |
Gynaecomastia | 1.23 (0.08) | 1.46 (0.15) | 1.46 (0.12) | 0.0005 |
Libido | 1.83 (0.16) | 3.00 (0.20) | 3.10 (0.18) | <0.0001 |
Male identity | 1.96 (0.96) | 3.28 (0.74) | 3.00 (1.07) | 0.0011 |
Depressive mood | 1.77 (0.16) | 1.54 (0.13) | 1.77 (0.16) | 0.8567 |
Spouse relationship | 1.32 (0.10) | 1.64 (0.18) | 1.48 (0.16) | 0.2332 |
Urinary frequency | 2.25 (0.89) | 2.15 (0.73) | 2.00 (0.82) | 0.0425a |
Other items worsened, this item improved significantly.