TABLE 4.
Mean FEV1 (ml) across quintiles of energy adjusted intake of total fiber, stratified by sex, ethnicity, and smoking status (1987-1989) *
No. of subjects | Quintiles of energy-adjusted intake of total fiber | Difference in FEV1 (ml) between quintiles 5 and 1 (95% CI) | p value for trend† | p value for interaction‡ | |||||
---|---|---|---|---|---|---|---|---|---|
1 (lowest) | 2 | 3 | 4 | 5 | |||||
Sex | |||||||||
Female | 6,799 | 2,325 | 2,337 | 2,354 | 2,376 | 2,369 | 44.0 (7.2,80.9) | 0.006 | 0.394 |
Male | 5,098 | 3,208 | 3,234 | 3,238 | 3,279 | 3,287 | 79.8 (22.5,137.0) | 0.003 | |
Ethnicity | |||||||||
Black | 2,798 | 2,506 | 2,524 | 2,550 | 2,557 | 2,575 | 68.4 (5.3,131.5) | 0.021 | 0.612 |
White | 9,099 | 2,860 | 2,877 | 2,880 | 2,921 | 2,921 | 60.7 (22.7,98.7) | <0.001 | |
Smoking status | |||||||||
Never | 5,174 | 2,771 | 2,779 | 2,785 | 2,821 | 2,822 | 50.7 (6.8,94.5) | 0.005 | 0.903 |
Current/past | 6,723 | 2,695 | 2,719 | 2,734 | 2,759 | 2,759 | 64.2 (17.2,111.1) | 0.003 |
Covariates included age, sex, height, square of height, study center, ethnicity, smoking status (current smoker, former smoker with ETS, former smoker without ETS, never smoker with ETS, never smoker without ETS), pack years, BMI, occupation, education, diabetes status, traffic density, total energy intake, glycemic index, micronutrients (carotenoids, vitamins C, D, E, and omega-3 fatty acids) from both food and supplements, and cured meat.
Tests for linear trends across increasing quintiles of fiber intake used the median values in each quintile.
Likelihood ratio test for interaction (effect modification) by sex, ethnicity, and smoking status.