Table 5.
Adjusted ORs for COPD across quintiles of energy adjusted intake of total fiber, stratified by sex, ethnicity, and smoking status *
| No. of subjects/cases | Quintiles of energy-adjusted intake of total fiber | p value for trend† | p value for interaction‡ | |||||
|---|---|---|---|---|---|---|---|---|
| 1(lowest) | 2 | 3 | 4 | 5 | ||||
| Sex | ||||||||
| Female | 6,799/756 | 1 | 1.01 (0.77, 1.33) | 0.90 (0.68,1.19) | 0.84 (0.62,1.13) | 0.92 (0.67,1.28) | 0.455 | 0.429 |
| Male | 5,098/997 | 1 | 1.01 (0.80,1.26) | 0.90 (0.71,1.15) | 0.83 (0.63,1.07) | 0.77 (0.57,1.03) | 0.041 | |
| Ethnicity | ||||||||
| Black | 2,798/307 | 1 | 1.00 (0.68,1.47) | 1.18 (0.79,1.75) | 1.00 (0.63,1.58) | 1.32 (0.81,2.15) | 0.300 | 0.003 |
| White | 9,099/1,446 | 1 | 1.01 (0.84,1.23) | 0.85 (0.70,1.05) | 0.81 (0.65,1.00) | 0.79 (0.62,1.00) | 0.016 | |
| Smoking status | ||||||||
| Never | 5,174/291 | 1 | 1.17 (0.76,1.80) | 0.97 (0.62,1.50) | 1.02 (0.65,1.59) | 1.13 (0.70,1.84) | 0.772 | 0.275 |
| Current/past | 6,723/1,462 | 1 | 0.99 (0.82,1.19) | 0.90 (0.73,1.10) | 0.79 (0.63,0.98) | 0.78 (0.61,0.99) | 0.013 | |
COPD defined by either chronic bronchitis (n=669) or spirometry-defined COPD (n=1,321) or both (n=1,753). Covariates included age, sex, study center, ethnicity, smoking status (current smoker, former smoker with ETS, former smoker without ETS, never smoker with ETS, never smoker without ETS), pack years, BMI, occupation, education, diabetes status, traffic density, total energy intake, glycemic index, micronutrients (carotenoids, vitamins C, D, E, and omega-3 polyunsaturated fatty acids) from both food and supplements, and cured meat.
Tests for linear trends across increasing quintiles of fiber intake used the median values in each quintile.
Likelihood ratio test for interaction (effect modification) by sex, ethnicity, and smoking status.