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Ki values determined with (S)-flurbiprofen as the substrate probe
| Inhibitor | Supersomes™ Ki (μM) |
HLM Ki (μM) |
RECO® Ki (μM) |
|---|---|---|---|
| Benzbromarone | 0.004 | 0.011 | 0.11 |
| Diclofenac | 1.6 | 2.9 | 9.3 |
| Fluvoxamine | 0.63 | 5.7 | 6.6 |
| Gemfibrozil | 12.4 | 0.98 | 13.9 |
| (S)-Ibuprofen | 4.3 | 3.2 | 17.1 |
| Indomethacin | 53.4 | 12.8 | 48.7 |
| Ketoconazole | 0.38 | 2.1 | 2.4 |
| Miconazole | 0.028 | 0.038 | 0.11 |
| Phenytoin | 5.6 | 10.2 | 11.1 |
| Piroxicam | 0.47 | 9.8 | 6.7 |
| Sulphaphenazole | 0.06 | 0.15 | 1.3 |
| Tolbutamide | 1.5 | 3.5 | 2.0 |
