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. Author manuscript; available in PMC: 2008 May 12.
Published in final edited form as: Biochemistry. 2007 Aug 17;46(36):10237–10247. doi: 10.1021/bi700876a

Figure 6. Comparison of the active sites of CYP2J2 and CYP2C9.

Figure 6

The active site cavities for CYP2C9 (pdb 1r9o) and CYP2J2 model were calculated using VOIDOO (42) and are represented as grey mesh. The heme is rendered in sticks and F and I helices as ribbons. The arrows indicate the width of the active site cavity available to the substrate in close proximity to the heme.