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. Author manuscript; available in PMC: 2008 May 12.
Published in final edited form as: Biochemistry. 2007 Aug 17;46(36):10237–10247. doi: 10.1021/bi700876a

Figure 8. Schematic positioning of terfenadone, 1, in the active site of CYP2J2.

Figure 8

Hydrophobic interactions are shown in red, the hydrogen bond between the keto function of 1 and Arg117 is drawn in blue, and putative polar interaction with Thr488 is represented in green.