Table 2. Relationship between detection of VEGF-C, VEGF-D and VEGFR-3 and clinico-pathological factors in ovarian carcinoma.

Factors	No. of patients	No. (%) of VEGF-C positive case	P-value	No. (%) of VEGF-D positive case	P-value	No. (%) of VEGFR-3 positive case	P-value
Peritoneal metastasis outside the pelvis
Negative	39	22(56.4)		21(53.8)		20(51.3)
Positive	20	17(85.0)	0.03	16(80.0)	0.04	16(80.0)	0.03
Lymph node metastasis
Negative	44	25(56.8)		24(54.5)		21(47.7)
Positive	15	14(93.3)	0.008	13(86.7)	0.02	15(100)	1E-04
Distant metastasis
Negative	55	35(63.6)		34(61.8)		33(60.0)
Positive	4	4(100)	NS	3(75.0)	NS	3(75.0)	NS
Age
⩽60	37	22(59.5)		22(59.5)		23(62.1)
60	22	17(77.3)	NS	15(68.2)	NS	13(59.1)	NS
Histology type
Serous	32	22(68.7)		22(68.7)		21(65.6)
Nonserous	27	17(63.0)	NS	15(55.6)	NS	15(55.6)	NS
Histological grade
Well	36	22(61.1)		21(58.3)		19(52.8)
Moderate	15	11(73.3)		10(66.7)		12(80.0)
Poor	8	6(75.0)	NS	6(75.0)	NS	5(62.5)	NS
VEGFR-3
Negative	23	11(47.8)		10(43.5)		—
Positive	36	28(77.8)	0.02	27(75.0)	0.02	—