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. 2003 Jan 28;88(2):291–297. doi: 10.1038/sj.bjc.6600680

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Copyright © 2003 Cancer Research UK

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Blood perfusion vs distance from tumour centre in A-07 and R-18 tumours. Na^99mTcO₄ was administered intravenously to tumour-bearing mice. The mice were killed and the tumours were frozen in liquid nitrogen 45 s after the administration of Na^99mTcO₄. The concentration of Na^99mTcO₄ in the tumour tissue was used as a parameter for blood perfusion. Tumour size was normalised, that is, tumour radius was assigned a value of 1.0. Blood perfusion was also normalised, that is, the mean concentration of Na^99mTcO₄ in each tumour section was assigned a value of 1.0. One section was analysed for each tumour. Points represent mean values of 8 (A-07) or 7 (R-18) tumours. Bars represent s.e.m.