Table 5. Relationship between the different biomarkers using Spearman's correlation coefficient (r).
|
Melanoma (20 cases) |
Colorectal carcinoma (16 cases) |
|||
|---|---|---|---|---|
| r | P | r | P | |
| Before culture | ||||
| TIL Fas vs tumour FasL | 0.51 | <0.05 | ||
| TIL Fas vs tumour Bax | −0.49 | <0.05 | −0.45 | <0.05 |
| TIL after culture | ||||
| Fas vs ζ chain | 0.63 | <0.01 | ||
| Fas vs p56lck | 0.57 | <0.01 | 0.69 | <0.01 |
| FasL vs ζ chain | 0.59 | <0.01 | ||
| FasL vs ɛ chain | 0.61 | <0.01 | 0.49 | <0.05 |
| FasL vs p56lck | 0.57 | <0.01 | 0.52 | <0.05 |
| Perforin vs ζ chain | 0.64 | <0.01 | ||
| Perforin vs p56lck a | 0.79 | <0.01 | ||
a
13 cases.
Spearman's correlation coefficient was calculated for each different TIL and tumour cell biomarker. Only statistically significant correlations are shown.