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| 150 mg m−2 a | 200 mg m−2 a | 250 mg m−2 a | 200 mg m−2 adj.a,b | |
|---|---|---|---|---|
| No. of patients | 6 | 18 | 18 | 32 |
| Thrombocytopenia | ||||
| Grade 3 | 0 | 0 | 5 | 1 |
| Grade 4 | 0 | 0 | 4 | 2 |
| Lymphocytopenia | ||||
| Grade 3 | 2 | 5 | 8 | 12 |
| Grade 4 | 0 | 2 | 3 | 3 |
Oral administration for 5 days
Dose adjustments took place in the following cycles according to the degree of myelosuppression.
