Skip to main content
. 2003 Jan 28;88(2):263–269. doi: 10.1038/sj.bjc.6600747

Table 1. Percent distributions of the genotypes and pairwise linkage disequilibrium scores for three markers in the TH-INS-IGF2 region stratified by ethnicity.

  All racesa
Black
Caucasian
Hispanic
  Cases Controls Cases Controls Cases Controls Cases Controls
  N=178 (%) N=135 (%) N=96 (%) N=67 (%) N=40 (%) N=36 (%) N=37 (%) N=29 (%)
+1127 INS-PstI                
 CC 80 70 81 72 80 61 73 79
 CT 18 26 18 27 17 33 24 10
 TT 2 4 1 1 3 6 3 10
                 
−4217 TH-PstI                
 CC 13 17 8 5 25 33 14 25
 CT 43 31 39 20 47 42 43 36
 TT 44 52 53 75 28 25 43 39
                 
+3580 IGF2-MspI                
 GG 42 42 50 37 25 49 41 50
 AG 40 46 37 53 55 41 32 37
 AA 18 11 13 10 20 10 27 13
                 
Linkage disequilibrium score (D′)b                
+1127 INS-PstI and −4217 TH-PstI     0.76 1 1      
+1127 INS-PstI and +3580 IGF2-MspI     0.85 0.80 0.87      
−4217 TH-PstI and +3580 IGF2-MspI     0.49 0.45 0.31      
a

Subjects with mixed ethnicity were included here, but not in the race-specific columns.

b

D′ was determined with cases and controls combined.