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. 2003 May 13;88(10):1516–1521. doi: 10.1038/sj.bjc.6600934

Table 3. Comparison between IPM response and response to previous cytokine therapy.

Cytokines        
 IFN monotherapy 24      
 IFN combination therapy 9      
Median interval cytokines to commencing IPM 5.9 months   (1–62)  
         
  Cytokines IPM
Response        
 Adjuvant 1   0  
 PR 1   1  
 MR 3   8  
 SD 11   9  
 PD 15   13  
 NE 2   2  
PR or better One out of 30 (3%)   One out of 31 (3%)  
SD or better 15 out of 30 (50%)   18 out of 31 (58%)  
Symptomatic        
Response Six out of 25 (24%)   17 out of 28 (61%)  
         
Median progression-free interval        
Overall 3.9 months   4.4 months  
 (a) SD or better 10.2 months   6.9 months  
 (b) PD 2.4 months   1.9 months  
P-value (a vs b) <0.001   <0.001  
 (c) Symptomatic response 10.2 months   6.2 months  
 (d) No symptomatic response 3.7 months   1.8 months  
P-value (c vs d) 0.09   <0.001  
         
Symptomatic response to cytokines vs IPM   Cytokine symptomatic response
    No Yes Total
IPM symptomatic response No 4 1 5
  Yes 11 5 16
  Total 15 6 21