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. 2003 May 13;88(10):1584–1586. doi: 10.1038/sj.bjc.6600944

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Copyright © 2003 Cancer Research UK

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Detection of bak mutations in cervical carcinoma by cold-SSCP and direct sequencing. (A) Cold-SSCP profiles. PCR products from tumour DNA were run alongside a wild-type (WT) control (human lymphocyte DNA). Bands showing altered mobility were observed in six cervical cancer cases (M17, 28, 34 for exon 3, M21, 31 for exon 4 and M38 for exon 6). (B) Sequencing profiles of the bands showing altered mobility on the SSCP gel. Arrows indicate the bases altered from wild type to mutant type.