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. 2003 May 13;88(10):1584–1586. doi: 10.1038/sj.bjc.6600944

Table 1. Mutations in coding region of the bak gene in cervical carcinoma.

        Mutations at
  Stage No. of cases Cases with mutation exon 3 exon 4 exon 6
Cancerous tissues II 12 1 1a 0 0
  III 30 5 3b 2c 1d
Total 42 6e 4 2 1
Non-neoplastic tissues 32 0 0 0 0
a

Codon 60 (ATG→GTG: Met→Val).

b

Codon 30 (GAC→AAC: Asp→Asn)+codon 57 (GAC→AAC: Asp→Asn), codon 59 (GAG→GAA: Glu→Glu).

c

Codon 74 (GTG→ATG: Val→Met), codon 80 (ATC→ACC: Leu→Thr).

d

Codon 191 (GTG→GCG: Val→Ala).

e

P<0.05 vs control by Fisher's exact test.