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. 2003 May 13;88(10):1522–1526. doi: 10.1038/sj.bjc.6600938

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Copyright © 2003 Cancer Research UK

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The plasma MK level becomes elevated with advancing neuroblastoma stages. The plasma MK level in children without malignant tumours was 205 pg ml⁻¹ (median, n=17). Those at stages 1, 2, 3, 4, and 4S were 445 (n=73), 589 (n=39), 864 (n=40), 1445 (n=50), and 2439 (n=12), respectively. The percentage of cases showing more than the cutoff value (500 pg ml⁻¹) is shown in parentheses beneath each stage. The plasma MK level is significantly elevated at all neuroblastoma stages compared with the normal level. Statistical analysis is summarised in Table 2.