Table 5. Clinical and immunocytochemical findings in 19 pheochromocytomas.
Clinical outcome |
ICC findings |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Case no. | Age | Sex | Malignant/benign | Hormonal syndrome | Years | NED | AWD | DWD | DOD | NESP55 | CgA |
55 | 47 | F | Benign | Yes | 8 | X | 0 | 0 | 0 | 3+ | 3+ |
56 | 53 | M | Benign | Yes | 7 | X | 0 | 0 | 0 | 3+ | 3+ |
57 | 27 | F | Benign | Yes | 3 | X | 0 | 0 | 0 | 3+ | 3+ |
58 | 48 | M | Benign | Yes | 8 | X | 0 | 0 | 0 | 3+ | 3+ |
59 | 52 | M | Benign | Yes | 4 | X | 0 | 0 | 0 | 3+ | 3+ |
60 | 73 | M | Benign | Yes | 1 | X | 0 | 0 | 0 | 3+ | 3+ |
61 | 52 | M | Benign | Yes | 1 | X | 0 | 0 | 0 | 3+ | 3+ |
62a | 38 | F | Benign | No | 2 | X | 0 | 0 | 0 | 3+ | 3+ |
63 | 47 | F | Benign | Yes | 3 | X | 0 | 0 | 0 | 2+ | 3+ |
64 | 20 | F | Benign | Yes | 2 | X | 0 | 0 | 0 | 3+ | 3+ |
65b | 18 | M | Benign | Yes | 1 | X | 0 | 0 | 0 | 3+ | 3+ |
66c | 20 | F | Benign | Yes | 7 | X | 0 | 0 | 0 | 2+ | 3+ |
67 | 61 | F | Benign | Yes | 4 | X | 0 | 0 | 0 | 1+ | 3+ |
68 | 56 | M | Benign | Yes | 2 | X | 0 | 0 | 0 | 3+ | 3+ |
69 | 76 | F | Malignant | Yes | 8 | 0 | 0 | X | 0 | 3+ | 3+ |
70 | 36 | F | Malignant | No | 23 | 0 | 0 | 0 | X | 3+ | 3+ |
71 | 55 | M | Malignant | No | 14 | X | 0 | 0 | 0 | 3+ | 3+ |
72 | 58 | M | Malignant | Yes | 1 | 0 | 0 | X | 0 | 3+ | 3+ |
73 | 61 | M | Malignant | Yes | 9 | 0 | 0 | X | 0 | 3+ | 3+ |
Age=age at diagnosis and primary surgery. F=female, M=male. Clinical outcome: Years=observation time. X indicates outcome at follow up, which was categorized as NED=alive, no evidence of disease. AWD=alive with disease. DWD=dead with disease. DOD=dead of disease. ICC findings: The categories were as follows: 0=<1% positive cells, 1+=1–24% positive cells, 2+=25–75% positive cells, 3+=>75% positive cells.
Turner's syndrome,
Familial pheochromocytoma, genetic defect unknown.
MEN 2B syndrome.