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. 2003 Feb 18;88(4):599–605. doi: 10.1038/sj.bjc.6600722

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Copyright © 2003 Cancer Research UK

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(A) Selective cytotoxicity of 5F 203 to MCF-7 cells. Growth inhibition induced by 5F 203 was assessed by sulphforhodamine B assay as detailed in Materials and Methods. Values are means±s.d. (n=10). (B) 5F 203 induces changes in nuclear morphology of 5F 203-sensitive MCF-7 breast cells but not AH^R100 cells. Cells prepared as described in Materials and Methods were exposed for 24 h to 0.1% DMSO (control) or 1 μM 5F 203, and stained with 4,6-diamidino-2-phenylindole (DAPI).