Fig. 4.
Pharmacological profile of OGD-activated maxi-anion channel events in inside-out patches excised from astrocytes. a Representative current traces recorded during application of alternating pulses (the protocol shown in inset above) in the absence (control) and presence of Gd3+ (50 μM in the pipette), arachidonic acid (20 μM in the bath), and phloretin (100 μM in the bath). b Effects of Gd3+, arachidonic acid, and phloretin on the OGD-induced single-channel activity recorded at ± 25 mV. Data are normalized to the mean currents before application of drugs. Each column represents the mean ± SEM (vertical bar). *Significantly different from the control value at P < 0.05