Table 2. Distribution of fitness effects under various best-fit selective models.
Population ancestry | African | African | European | European | European | African | European | European |
Demographic model | expansion | expansion | complex bottleneck | complex bottleneck | complex bottleneck | stationary | stationary | simple bottleneck |
Selection model | gamma | lognormal | gamma | lognormal | exp+neut | gamma | gamma | gamma |
|s|<0.00001 | 27.9% | 28.4% | 24.3% | 24.6% | 25.0% | 22.2% | 35.7% | 23.5% |
0.00001<|s|<0.0001 | 14.7% | 14.3% | 14.7% | 15.7% | 0.9% | 48.2% | 38.7% | 16.1% |
0.0001<|s|<0.01 | 21.9% | 15.4% | 23.1% | 17.5% | 53.7% | 29.6% | 25.4% | 26.1% |
|s|>0.01 | 35.5% | 41.9% | 37.9% | 42.3% | 20.5% | 0.0% | 0.2% | 34.3% |
Proportion of mutations falling into each selection interval for each population under each best-fit models. Demographic model parameters are listed in Table 3; selection model parameters are listed in Table 1 except for African American stationary gamma (α = 0.59, β = 37), and European American stationary gamma (α = 0.36, β = 120), and European American simple bottleneck gamma (α = 0.228, β = 5200).