Table 5. A comparison of several recent estimates of the DFE at nonsynonymous sites in humans.
this study | Eyre-Walker et al. [11] | Yampolsky et al. [10] | |||
African American (gamma distribution) | European American (gamma distribution) | basic gamma distribution | gamma with demographic correction | ||
s<0.00001 | 18% | 15% | 11% | 10% | 12% |
0.00001<s<0.0001 | 10% | 9% | 8% | 10% | 14% |
0.0001<s<0.01 | 37% | 38% | 37% | 37% | 49% |
0.01<s | 36% | 38% | 44% | 29% | 25% |