Table 1.
Summary of quadruplex occurrences in upstream regions of the human genome
| Quadruplex occurences | Number of genes | Number of sequence elements |
|---|---|---|
| SP1 sequence elements which occur in upstream regions | 11 872 | 29 991 |
| PQSSs in upstream regions which contain SP1 sequence elements | 5415 | 8660 |
| Genes without SP1 consensus sequence in their upstream regions | 10 761 | |
| PQSSs in upstream regions which do not contain SP1 sequence elements | 1096 | 1335 |
| PQSSs which incorporate SP1 sequence elements and are within upstream regions | 3596 | 4721 |
| PQSSs which do not incorporate SP1 sequence elements and are within upstream regions | 4150 | 5274 |
| CCAAT sequence elements which occur in upstream regions | 10 963 | 17 574 |
| PQSSs in upstream regions containing CCAAT sequence elements | 2718 | 3948 |
| Genes whose upstream regions contain no CCAAT sequence elements | 11 670 | |
| PQSSs in upstream regions containing no CCAAT sequence elements | 3794 | 6047 |
| Genes whose upstream regions contain CCAAT and SP1 | 5451 | |
| PQSSs in upstream regions containing SP1 and CCAAT sequence elements | 2236 | 3368 |
| Genes whose upstream regions contain CCAAT and no SP1 | 5512 | |
| PQSSs in upstream regions containing CCAAT and no SP1 sequence elements | 482 | 580 |
| Genes whose upstream regions contain SP1 and no CCAAT | 6421 | |
| PQSSs in upstream regions containing SP1 and no CCAAT elements | 3180 | 5292 |
| Genes whose upstream regions contain neither SP1 nor CCAAT | 5249 | |
| PQSSs in upstream regions containing neither SP1 nor CCAAT elements | 614 | 755 |
| All genes | 22 633 | |
| PQSSs in all upstream regions | 6512 | 9995 |