Table 1.
Tissue specificity of DNA words and their association with known transcription factors
| DNA Word | Factor | Enriched Tissues | P-value (expression similarity) | P-value (GO functional similarity) |
|---|---|---|---|---|
| CCGGAAGC | Sp1, c-Ets-1, Ets-1, GABP-alpha, GABP-beta, STAT1, STAT3 | PBCD4+Tcells, PBCD8+Tcells, Prostate | 1.00E-06 | 3.24E-03 |
| CGCGATGG | Egr-1 | Adrenal gland | 1.00E-06 | 1.49E-02 |
| GCCGCCAT | YY-1 | PBCD4+Tcells, PBCD8+Tcells | 1.00E-06 | 4.30E-05 |
| GCCTGCGC | NRF1, Sp1, Sp3 | Thyroid | 1.00E-06 | 8.88E-03 |
| GGCGGGGC | Sp1, Sp3, NF-Y | Amygdala, Prostate | 1.00E-06 | 7.42E-03 |
| GGTCACGT | Sp1, Sp3, ATF-1 | PLACENTA | 1.00E-06 | 1.81E-02 |
| TTCCGCGC | E2F1, Sp3 | PBCD4+Tcells, PBCD8+Tcells, Thymus | 2.20E-02 | 2.24E-02 |
The last columns give the P-values of clusters (estimated by simulation from microarray data and GO-derived functional similarity data). The rows in the table reflect the lexicographic order of the words in column 1.