Table 3.
TFBS words corresponding to two clusters, whose gene groups have significantly different microarray expression patterns
| DNA Word | Factor | Distance from TSS (bp) | P-value |
|---|---|---|---|
| CCCCGCCC | c-Myc, AP-2alphaA, E2F-1, NF-AT1, MAZ | −65, −20 | 2.24E-04 |
| CCGCCGCC | YY1, Egr-1, AP-2alphaA, Sp1, Sp3 | 63, 13 | 4.18E-02 |
| CGCCCCGC | Sp1, Sp3, E2F-1, Egr-1 | −176, 41 | 4.04E-02 |
| CGCCGCTG | Unidentified | 15, 39 | 4.66E-04 |
| CGGGCGGC | DP-1, E2F:DP, Sp1, GKLF | −15, 23 | 1.16E-07 |
| GAGGCGGC | Unknown | −16, 20 | 2.85E-02 |
| GGGCGGCG | Sp1, NF-Y, GKLF | −20, 143 | 1.15E-11 |
The rows in the table reflect the lexicographic order of the words in column 1. Each word corresponds to TFs in column 2. Each word corresponds to two clusters, whose average positions relative to the TSS are in column 3. Fisher inverse chi-squared test yielded a (multiple test corrected) two-sided P-value (in column 4), which quantifies the overall differences in expression between the gene group pair in the 74 tissues.