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. 2008 Mar 16;36(8):2654–2666. doi: 10.1093/nar/gkn112

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — The A1555G mutant of the H. sapiens mitochondrial A site in the second ‘off’ state. (a) Secondary structure and stereoview. (b–h) Atomic details of each base pair of the A site. Three universally conserved adenine residues, A1492, A1557 and A1558 (A1408, A1492 and A1493 in bacterial numbering), are colored in orange, blue and red, respectively. Two nucleotides different from those in bacterial A site, G1555 and C1556 (G1490 and C1491 in bacterial numbering), are colored in cyan and green, respectively. The hydrogen bonds are represented by black dashed lines.