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. 2008 Mar 16;36(8):2654–2666. doi: 10.1093/nar/gkn112

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Stereoviews of interactions among the A site, mRNA (orange) and tRNA (sky blue). (a) The T. thermophilus ribosome [PDBID: 2j00 in (8)]. (b) The H. sapiens mitochondrial A site superposed on the T. thermophilus ribosomal A site. The A sites have the ‘on’ and ‘off’ states in (a) and (b), respectively. Three universally conserved adenine residues, A1492, A1557 and A1558 (A1408, A1492 and A1493 in bacterial numbering), are colored in orange, blue and red, respectively. Two nucleotides different in the bacterial and mitochondrial A sites, residues 1555 and 1556 (1490 and 1491 in bacterial numbering), are colored in cyan and green, respectively.