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Predicted loops critical for adhesion to VCAM-1 and CS-1 are shown to be adjacent in the upper face of the predicted β-propeller structure of α4. Views are (a) from the top and (b) from the side. The predicted β-propeller structure was taken from (14). ∗, Predicted loops critical for adhesion. Residues 181–191 include both R3b and R3c mutants.
